Clinico-Radiographic spectrum of cleidocranial dysplasia: A case series

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Cleidocranial Dysplasia: A Clinico-radiographic Spectrum with Differential Diagnosis

INTRODUCTION Cleidocranial dysplasia (CCD) is characterized by aplasia or hypoplasia of the clavicles, characteristic craniofacial malformations, and the presence of numerous supernumerary and unerupted teeth. It affects bones derived from both intra-membranous and endochondral ossification. Incidence has been reported as 1 in 10,00,000. It is caused by mutation in the gene encoding transcripti...

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Cleidocranial dysplasia: clinico-radiological illustration of a rare case.

Cleidocranial dysplasia is an autosomal dominant condition caused by mutation of RUNX2, characterized by generalized dysplasia of the bones and teeth. Affected individuals have short stature, atypical facial features, and skeletal anomalies affecting mainly the skull and clavicle. The dental manifestations are mainly delayed exfoliation of the primary teeth and delayed eruption of the permanent...

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Familial Cleidocranial Dysplasia - A Case Series

Introduction: Cleidocranial dysplasia is a rare hereditary autosomal dominant disorder which presents as a defect of the skeleton and the teeth. Case Report: The present case is of a 37 year old male patient with a complaint of difficulty in chewing due to multiple missing teeth. On examination, the pathognomonic triad of Cleidocranial Dysplasia, viz., multiple impacted supernumerary teeth, par...

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Clinical spectrum of cleidocranial dysplasia: a case report

BACKGROUND Cleidocranial dysplasia is a developmental anomaly of the skeleton and the teeth. This condition may be inherited, be transmitted as dominant characteristics in either sex, or even may appear spontaneously. It presents with skeletal defects of several bones, like partial or complete absence of clavicles, late closure of the fontanels, presence of open skull sutures and multiple wormi...

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[Cleidocranial dysplasia: a case report].

A 3-month-old female infant who presented with patent sagittal suture and loss of weight is described. Physical examination revealed a large sagittal and metopic suture showing delayed closure, a high-arched palate, saddle nose, hypertelorism and nonpalpable edges of the bilateral clavicles. The clavicles also showed undue mobility. Radiological investigations of the cranial skeletal abnormalit...

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ژورنال

عنوان ژورنال: Indian Journal of Case Reports

سال: 2020

ISSN: 2454-129X,2454-1303

DOI: 10.32677/ijcr.2020.v06.i11.001